Cargando…

Enantioselective Construction of Tertiary Fluoride Stereocenters by Organocatalytic Fluorocyclization

[Image: see text] 1,1-Disubstituted styrenes with internal oxygen and nitrogen nucleophiles undergo oxidative fluorocyclization reactions with in situ generated chiral iodine(III)-catalysts. The resulting fluorinated tetrahydrofurans and pyrrolidines contain a tertiary carbon–fluorine stereocenter....

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qiang, Lübcke, Marvin, Biosca, Maria, Hedberg, Martin, Eriksson, Lars, Himo, Fahmi, Szabó, Kálmán J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735711/
https://www.ncbi.nlm.nih.gov/pubmed/33191747
http://dx.doi.org/10.1021/jacs.0c09323