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Cholesterol Reduces Partitioning of Antifungal Drug Itraconazole into Lipid Bilayers
[Image: see text] Cholesterol plays a crucial role in modulating the physicochemical properties of biomembranes, both increasing mechanical strength and decreasing permeability. Cholesterol is also a common component of vesicle-based delivery systems, including liposome-based drug delivery systems (...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735721/ https://www.ncbi.nlm.nih.gov/pubmed/32101005 http://dx.doi.org/10.1021/acs.jpcb.9b11005 |