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Cholesterol Reduces Partitioning of Antifungal Drug Itraconazole into Lipid Bilayers

[Image: see text] Cholesterol plays a crucial role in modulating the physicochemical properties of biomembranes, both increasing mechanical strength and decreasing permeability. Cholesterol is also a common component of vesicle-based delivery systems, including liposome-based drug delivery systems (...

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Detalles Bibliográficos
Autores principales: Poojari, Chetan, Zak, Agata, Dzieciuch-Rojek, Monika, Bunker, Alex, Kepczynski, Mariusz, Róg, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735721/
https://www.ncbi.nlm.nih.gov/pubmed/32101005
http://dx.doi.org/10.1021/acs.jpcb.9b11005