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Emergence of Barrel Motif in Amyloid-β Trimer: A Computational Study
[Image: see text] Amyloid-β (Aβ) peptides form assemblies that are pathological hallmarks of Alzheimer’s disease. Aβ oligomers are soluble, mobile, and toxic forms of the peptide that act in the extracellular space before assembling into protofibrils and fibrils. Therefore, oligomers play an importa...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735726/ https://www.ncbi.nlm.nih.gov/pubmed/33180492 http://dx.doi.org/10.1021/acs.jpcb.0c05508 |