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Viral-induced alternative splicing of host genes promotes influenza replication

Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that infection of human lung epithelial cells with influenza A virus (IAV) also induces a broad program of alternative splicing of host genes. Although these splicing-regulated genes are...

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Detalles Bibliográficos
Autores principales: Thompson, Matthew G, Dittmar, Mark, Mallory, Michael J, Bhat, Prasanna, Ferretti, Max B, Fontoura, Beatriz MA, Cherry, Sara, Lynch, Kristen W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735754/
https://www.ncbi.nlm.nih.gov/pubmed/33269701
http://dx.doi.org/10.7554/eLife.55500