Enhanced Anti-Cancer Effect of Folate-Conjugated Olaparib Nanoparticles Combined with Radiotherapy in Cervical Carcinoma

BACKGROUND: Radiotherapy (RT), one of the main treatments for cervical cancer, has tremendous potential for improvement in the efficacy. Poly (ADP-ribose) polymerase (PARP) is a key enzyme in the repair of DNA strand breaks (DSB). Olaparib (Ola) is a PARP inhibitor that is involved in preventing the...

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Detalles Bibliográficos
Autores principales: Li, Dong, Hu, Chuanfei, Yang, Juan, Liao, Yin, Chen, Yue, Fu, Shao Zhi, Wu, Jing Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735794/
https://www.ncbi.nlm.nih.gov/pubmed/33328733
http://dx.doi.org/10.2147/IJN.S272730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735794/
https://www.ncbi.nlm.nih.gov/pubmed/33328733
http://dx.doi.org/10.2147/IJN.S272730

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