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The Orai1 inhibitor BTP2 has multiple effects on Ca(2+) handling in skeletal muscle

BTP2 is an inhibitor of the Ca(2+) channel Orai1, which mediates store-operated Ca(2+) entry (SOCE). Despite having been extensively used in skeletal muscle, the effects of this inhibitor on Ca(2+) handling in muscle cells have not been described. To address this question, we used intra- and extrace...

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Detalles Bibliográficos
Autores principales: Meizoso-Huesca, Aldo, Launikonis, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735889/
https://www.ncbi.nlm.nih.gov/pubmed/33316029
http://dx.doi.org/10.1085/jgp.202012747