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Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood

Alzheimer’s disease (AD) is associated with disturbances in blood glucose regulation, and type-2 diabetes elevates the risk for dementia. A role for amyloid-β peptide (Aβ) in linking these age-related conditions has been proposed, tested primarily in transgenic mouse lines that overexpress mutated a...

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Detalles Bibliográficos
Autores principales: Hendrix, Rachel D., Ou, Yang, Davis, Jakeira E., Odle, Angela K., Groves, Thomas R., Allen, Antiño R., Childs, Gwen V., Barger, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736209/
https://www.ncbi.nlm.nih.gov/pubmed/33161213
http://dx.doi.org/10.1016/j.neurobiolaging.2020.10.001