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CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion
Calcium/calmodulin-dependent protein serine kinase (CASK) is a key player in vesicle transport and release in neurons. However, its precise role, particularly in nonneuronal systems, is incompletely understood. We report that CASK functions as an important regulator of insulin secretion. CASK deplet...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736295/ https://www.ncbi.nlm.nih.gov/pubmed/33318489 http://dx.doi.org/10.1038/s41421-020-00216-3 |