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Sirtuin 1-dependent regulation of high mobility box 1 in hypoxia–reoxygenated brain microvascular endothelial cells: roles in neuronal amyloidogenesis

Hypoxia–reperfusion injury is one of the major risk factors for neurodegeneration. However, it is unclear whether ischaemic damage in brain microvascular endothelial cells plays roles in neurodegeneration, particularly in the amyloidogenic changes contributing to the development of Alzheimer’s disea...

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Detalles Bibliográficos
Autores principales: Lee, Young-Sun, Choi, Ji-Young, Mankhong, Sakulrat, Moon, Sohee, Kim, Sujin, Koh, Young Ho, Kim, Ji-Hye, Kang, Ju-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736319/
https://www.ncbi.nlm.nih.gov/pubmed/33318474
http://dx.doi.org/10.1038/s41419-020-03293-0