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Biochemical phenotyping of multiple myeloma patients at diagnosis reveals a disorder of mitochondrial complexes I and II and a Hartnup-like disturbance as underlying conditions, also influencing different stages of the disease

The aim of this study was to identify novel plasma metabolic signatures with possible relevance during multiple myeloma (MM) development and progression. A biochemical quantitative phenotyping platform based on targeted electrospray ionization tandem mass spectrometry technology was used to aid in t...

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Detalles Bibliográficos
Autores principales: da Silva, Ismael Dale Cotrim Guerreiro, de Castro Levatti, Erica Valadares, Pedroso, Amanda Paula, Marchioni, Dirce Maria Lobo, Carioca, Antonio Augusto Ferreira, Colleoni, Gisele Wally Braga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736334/
https://www.ncbi.nlm.nih.gov/pubmed/33318510
http://dx.doi.org/10.1038/s41598-020-75862-4