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Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells

Background: Endothelial function significantly depends on the proteolytic release of surface expressed signal molecules, their receptors and adhesion molecules via the metalloproteinase ADAM17. The pseudoproteases iRhom1 and 2 independently function as adapter proteins for ADAM17 and are essential f...

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Detalles Bibliográficos
Autores principales: Babendreyer, Aaron, Rojas-González, Diana M., Giese, Anja Adelina, Fellendorf, Sandra, Düsterhöft, Stefan, Mela, Petra, Ludwig, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736406/
https://www.ncbi.nlm.nih.gov/pubmed/33335915
http://dx.doi.org/10.3389/fcvm.2020.610344