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Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells
Background: Endothelial function significantly depends on the proteolytic release of surface expressed signal molecules, their receptors and adhesion molecules via the metalloproteinase ADAM17. The pseudoproteases iRhom1 and 2 independently function as adapter proteins for ADAM17 and are essential f...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736406/ https://www.ncbi.nlm.nih.gov/pubmed/33335915 http://dx.doi.org/10.3389/fcvm.2020.610344 |