Minimal system for assembly of SARS-CoV-2 virus like particles

SARS-CoV-2 virus is the causative agent of COVID-19. Here we demonstrate that non-infectious SARS-CoV-2 virus like particles (VLPs) can be assembled by co-expressing the viral proteins S, M and E in mammalian cells. The assembled SARS-CoV-2 VLPs possess S protein spikes on particle exterior, making...

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Detalles Bibliográficos
Autores principales: Swann, Heather, Sharma, Abhimanyu, Preece, Benjamin, Peterson, Abby, Eldredge, Crystal, Belnap, David M., Vershinin, Michael, Saffarian, Saveez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736577/
https://www.ncbi.nlm.nih.gov/pubmed/33318562
http://dx.doi.org/10.1038/s41598-020-78656-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736577/
https://www.ncbi.nlm.nih.gov/pubmed/33318562
http://dx.doi.org/10.1038/s41598-020-78656-w

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