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Improving the Predictive Value of Prion Inactivation Validation Methods to Minimize the Risks of Iatrogenic Transmission With Medical Instruments

Prions are pathogenic infectious agents responsible for fatal, incurable neurodegenerative diseases in animals and humans. Prions are composed exclusively of an aggregated and misfolded form (PrP(Sc)) of the cellular prion protein (PrP(C)). During the propagation of the disease, PrP(Sc) recruits and...

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Detalles Bibliográficos
Autores principales: Moudjou, Mohammed, Castille, Johan, Passet, Bruno, Herzog, Laetitia, Reine, Fabienne, Vilotte, Jean-Luc, Rezaei, Human, Béringue, Vincent, Igel-Egalon, Angélique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736614/
https://www.ncbi.nlm.nih.gov/pubmed/33335894
http://dx.doi.org/10.3389/fbioe.2020.591024