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Cepharanthine as a Potential Novel Tumor-Regional Therapy in Treating Cutaneous Melanoma: Altering the Expression of Cathepsin B, Tumor Suppressor Genes and Autophagy-Related Proteins

The incidence of primary cutaneous melanoma continues to increase annually and is one of the most aggressive malignancies in humans and need to develop more novel non-surgical therapies. Autophagy and cathepsin B targeted therapy was reported to improve melanoma treatment. Cepharanthine (CEP), a nat...

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Detalles Bibliográficos
Autores principales: Liu, Yufang, Xie, Yang, Lin, Yao, Xu, Qingfang, Huang, Yunfen, Peng, Mengran, Lai, Wei, Zheng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736638/
https://www.ncbi.nlm.nih.gov/pubmed/33335896
http://dx.doi.org/10.3389/fbioe.2020.601969