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In silico derived small molecules targeting the finger-finger interaction between the histone lysine methyltransferase NSD1 and Nizp1 repressor
PHD fingers are small chromatin binding domains, that alone or in tandem work as versatile interaction platforms for diversified activities, ranging from the decoding of the modification status of histone tails to the specific recognition of non-histone proteins. They play a crucial role in their ho...
Autores principales: | Berardi, Andrea, Ghitti, Michela, Quilici, Giacomo, Musco, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736721/ https://www.ncbi.nlm.nih.gov/pubmed/33363704 http://dx.doi.org/10.1016/j.csbj.2020.11.044 |
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