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Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation

Thousands of transcriptome data sets are available, but approaches for their use in dynamic cell response modelling are few, especially for processes affected simultaneously by two orthogonal influencing variables. We approached this problem for neuroepithelial development of human pluripotent stem...

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Detalles Bibliográficos
Autores principales: Meisig, Johannes, Dreser, Nadine, Kapitza, Marion, Henry, Margit, Rotshteyn, Tamara, Rahnenführer, Jörg, Hengstler, Jan G, Sachinidis, Agapios, Waldmann, Tanja, Leist, Marcel, Blüthgen, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736781/
https://www.ncbi.nlm.nih.gov/pubmed/33245762
http://dx.doi.org/10.1093/nar/gkaa1089