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Developmental remodelling of non-CG methylation at satellite DNA repeats

In vertebrates, DNA methylation predominantly occurs at CG dinucleotides however, widespread non-CG methylation (mCH) has been reported in mammalian embryonic stem cells and in the brain. In mammals, mCH is found at CAC trinucleotides in the nervous system, where it is associated with transcriptiona...

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Detalles Bibliográficos
Autores principales: Ross, Samuel E, Angeloni, Allegra, Geng, Fan-Suo, de Mendoza, Alex, Bogdanovic, Ozren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736785/
https://www.ncbi.nlm.nih.gov/pubmed/33271598
http://dx.doi.org/10.1093/nar/gkaa1135