Interstitial telomere sequences disrupt break-induced replication and drive formation of ectopic telomeres

Break-induced replication (BIR) is a mechanism used to heal one-ended DNA double-strand breaks, such as those formed at collapsed replication forks or eroded telomeres. Instead of utilizing a canonical replication fork, BIR is driven by a migrating D-loop and is associated with a high frequency of m...

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Detalles Bibliográficos
Autores principales: Stivison, Elizabeth A, Young, Kati J, Symington, Lorraine S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736798/
https://www.ncbi.nlm.nih.gov/pubmed/33264397
http://dx.doi.org/10.1093/nar/gkaa1081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736798/
https://www.ncbi.nlm.nih.gov/pubmed/33264397
http://dx.doi.org/10.1093/nar/gkaa1081

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