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Sequence dependent phase separation of protein-polynucleotide mixtures elucidated using molecular simulations

Ribonucleoprotein (RNP) granules are membraneless organelles (MLOs), which majorly consist of RNA and RNA-binding proteins and are formed via liquid–liquid phase separation (LLPS). Experimental studies investigating the drivers of LLPS have shown that intrinsically disordered proteins (IDPs) and nuc...

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Detalles Bibliográficos
Autores principales:	Regy, Roshan Mammen, Dignon, Gregory L, Zheng, Wenwei, Kim, Young C, Mittal, Jeetain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736803/ https://www.ncbi.nlm.nih.gov/pubmed/33264400 http://dx.doi.org/10.1093/nar/gkaa1099

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