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A unified model for the G1/S cell cycle transition

Efficient S phase entry is essential for development, tissue repair, and immune defences. However, hyperactive or expedited S phase entry causes replication stress, DNA damage and oncogenesis, highlighting the need for strict regulation. Recent paradigm shifts and conflicting reports demonstrate the...

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Detalles Bibliográficos
Autores principales: Hume, Samuel, Dianov, Grigory L, Ramadan, Kristijan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736809/
https://www.ncbi.nlm.nih.gov/pubmed/33166394
http://dx.doi.org/10.1093/nar/gkaa1002