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A unified model for the G1/S cell cycle transition
Efficient S phase entry is essential for development, tissue repair, and immune defences. However, hyperactive or expedited S phase entry causes replication stress, DNA damage and oncogenesis, highlighting the need for strict regulation. Recent paradigm shifts and conflicting reports demonstrate the...
Autores principales: | Hume, Samuel, Dianov, Grigory L, Ramadan, Kristijan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736809/ https://www.ncbi.nlm.nih.gov/pubmed/33166394 http://dx.doi.org/10.1093/nar/gkaa1002 |
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