PLEKHG5 regulates autophagy, survival and MGMT expression in U251-MG glioblastoma cells

A signalling pathway involving PLEKHG5 (guanine exchange factor) for the Ras superfamily member RAB26 to transcription factor NF-κB was discovered in autophagy. PLEKHG5 was reported in glioblastoma multiforme (GBM) and correlates with patient survival. Thus, the generation of a cellular model for un...

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Detalles Bibliográficos
Autores principales: Witte, Kaya Elisa, Slotta, Carsten, Lütkemeyer, Melanie, Kitke, Angelika, Coras, Roland, Simon, Matthias, Kaltschmidt, Christian, Kaltschmidt, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736842/
https://www.ncbi.nlm.nih.gov/pubmed/33318498
http://dx.doi.org/10.1038/s41598-020-77958-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736842/
https://www.ncbi.nlm.nih.gov/pubmed/33318498
http://dx.doi.org/10.1038/s41598-020-77958-3

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