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A highly sensitive method for the detection of recombinant PERV-A/C env RNA using next generation sequencing technologies

Several xenogenic cell-based therapeutic products are currently under development around the world for the treatment of human diseases. Porcine islet cell products for treating human diabetes are a typical example. Since porcine cells possess endogenous retrovirus (PERV), which can replicate in huma...

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Detalles Bibliográficos
Autores principales: Kono, Ken, Kataoka, Kiyoko, Yuan, Yuzhe, Yusa, Keisuke, Uchida, Kazuhisa, Sato, Yoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736861/
https://www.ncbi.nlm.nih.gov/pubmed/33318655
http://dx.doi.org/10.1038/s41598-020-78890-2