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Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss
Age-related hearing loss (AHL) is a progressive sensorineural hearing loss in elderly people. Although no prevention or treatments have been established for AHL, recent studies have demonstrated that oxidative stress is closely related to pathogenesis of AHL, suggesting that suppression of oxidative...
Autores principales: | Oishi, Tetsuya, Matsumaru, Daisuke, Ota, Nao, Kitamura, Hiroshi, Zhang, Tianxiang, Honkura, Yohei, Katori, Yukio, Motohashi, Hozumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736866/ https://www.ncbi.nlm.nih.gov/pubmed/33318486 http://dx.doi.org/10.1038/s41514-020-00053-4 |
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