The role of polygenic risk and susceptibility genes in breast cancer over the course of life

Polygenic risk scores (PRS) for breast cancer have potential to improve risk prediction, but there is limited information on their utility in various clinical situations. Here we show that among 122,978 women in the FinnGen study with 8401 breast cancer cases, the PRS modifies the breast cancer risk...

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Detalles Bibliográficos
Autores principales: Mars, Nina, Widén, Elisabeth, Kerminen, Sini, Meretoja, Tuomo, Pirinen, Matti, della Briotta Parolo, Pietro, Palta, Priit, Palotie, Aarno, Kaprio, Jaakko, Joensuu, Heikki, Daly, Mark, Ripatti, Samuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736877/
https://www.ncbi.nlm.nih.gov/pubmed/33318493
http://dx.doi.org/10.1038/s41467-020-19966-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736877/
https://www.ncbi.nlm.nih.gov/pubmed/33318493
http://dx.doi.org/10.1038/s41467-020-19966-5

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