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Elucidating the regulatory mechanism of Swi1 prion in global transcription and stress responses

Transcriptional regulators are prevalent among identified prions in Saccharomyces cerevisiae, however, it is unclear how prions affect genome-wide transcription. We show here that the prion ([SWI(+)]) and mutant (swi1∆) forms of Swi1, a subunit of the SWI/SNF chromatin-remodeling complex, confer dra...

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Detalles Bibliográficos
Autores principales: Du, Zhiqiang, Regan, Jeniece, Bartom, Elizabeth, Wu, Wei-Sheng, Zhang, Li, Goncharoff, Dustin Kenneth, Li, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736884/
https://www.ncbi.nlm.nih.gov/pubmed/33318504
http://dx.doi.org/10.1038/s41598-020-77993-0