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Variation of the human mu-opioid receptor (OPRM1) gene predicts vulnerability to frustration

Understanding the emotional reaction to loss, or frustration, is a critical problem for the field of mental health. Animal models of loss have pointed to the opioid system as a nexus of frustration, physical pain, and substance abuse. However, few attempts have been made to connect the results of an...

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Detalles Bibliográficos
Autores principales: Daniel, Alan M., Rushing, Brenda G., Tapia Menchaca, Karla Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736895/
https://www.ncbi.nlm.nih.gov/pubmed/33318511
http://dx.doi.org/10.1038/s41598-020-78783-4