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Convergent network effects along the axis of gene expression during prostate cancer progression

BACKGROUND: Tumor-specific genomic aberrations are routinely determined by high-throughput genomic measurements. It remains unclear how complex genome alterations affect molecular networks through changing protein levels and consequently biochemical states of tumor tissues. RESULTS: Here, we investi...

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Detalles Bibliográficos
Autores principales: Charmpi, Konstantina, Guo, Tiannan, Zhong, Qing, Wagner, Ulrich, Sun, Rui, Toussaint, Nora C., Fritz, Christine E., Yuan, Chunhui, Chen, Hao, Rupp, Niels J., Christiansen, Ailsa, Rutishauser, Dorothea, Rüschoff, Jan H., Fankhauser, Christian, Saba, Karim, Poyet, Cedric, Hermanns, Thomas, Oehl, Kathrin, Moore, Ariane L., Beisel, Christian, Calzone, Laurence, Martignetti, Loredana, Zhang, Qiushi, Zhu, Yi, Martínez, María Rodríguez, Manica, Matteo, Haffner, Michael C., Aebersold, Ruedi, Wild, Peter J., Beyer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737297/
https://www.ncbi.nlm.nih.gov/pubmed/33317623
http://dx.doi.org/10.1186/s13059-020-02188-9