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Competition for nutritional resources masks the true frequency of bacterial mutants

BACKGROUND: It is widely assumed that all mutant microorganisms present in a culture are able to grow and form colonies, provided that they express the features required for selection. Unlike wild-type Escherichia coli, PHO-constitutive mutants overexpress alkaline phosphatase and hence can hydrolyz...

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Detalles Bibliográficos
Autores principales: Neves, Henrique Iglesias, Machado, Gabriella Trombini, Ramos, Taíssa Cristina dos Santos, Yang, Hyun Mo, Yagil, Ezra, Spira, Beny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737367/
https://www.ncbi.nlm.nih.gov/pubmed/33317515
http://dx.doi.org/10.1186/s12915-020-00913-1