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Competition for nutritional resources masks the true frequency of bacterial mutants
BACKGROUND: It is widely assumed that all mutant microorganisms present in a culture are able to grow and form colonies, provided that they express the features required for selection. Unlike wild-type Escherichia coli, PHO-constitutive mutants overexpress alkaline phosphatase and hence can hydrolyz...
Autores principales: | Neves, Henrique Iglesias, Machado, Gabriella Trombini, Ramos, Taíssa Cristina dos Santos, Yang, Hyun Mo, Yagil, Ezra, Spira, Beny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737367/ https://www.ncbi.nlm.nih.gov/pubmed/33317515 http://dx.doi.org/10.1186/s12915-020-00913-1 |
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