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Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model

BACKGROUND: Previous studies noted that intravitreal injection of S100B triggered a glaucoma-like degeneration of retina and optic nerve as well as microglia activation after 14 days. The precise role of microglia in our intravitreal S100B model is still unclear. Hence, microglia were inhibited thro...

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Detalles Bibliográficos
Autores principales: Grotegut, Pia, Perumal, Natarajan, Kuehn, Sandra, Smit, Andreas, Dick, H. Burkhard, Grus, Franz H., Joachim, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737388/
https://www.ncbi.nlm.nih.gov/pubmed/33317557
http://dx.doi.org/10.1186/s12974-020-02012-y