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Defects at the Posttranscriptional Level Account for the Low TCRζ Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity

BACKGROUND: Reduced TCRζ chain surface has been reported in T cells from patients with different inflammatory conditions and cancer. However, the causes of this diminished expression in cancer remain elusive. METHODS: T cell-enriched populations of blood or tissue (tumoral and nontumoral) origin fro...

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Detalles Bibliográficos
Autores principales: Aguinaga-Barrilero, Ana, Castro-Sánchez, Patricia, Juárez, Ignacio, Gutiérrez-Calvo, Alberto, Rodríguez-Pérez, Noelia, Lopez, Adela, Gómez, Remedios, Martin-Villa, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737443/
https://www.ncbi.nlm.nih.gov/pubmed/33354577
http://dx.doi.org/10.1155/2020/1039458