Cargando…
Defects at the Posttranscriptional Level Account for the Low TCRζ Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity
BACKGROUND: Reduced TCRζ chain surface has been reported in T cells from patients with different inflammatory conditions and cancer. However, the causes of this diminished expression in cancer remain elusive. METHODS: T cell-enriched populations of blood or tissue (tumoral and nontumoral) origin fro...
Autores principales: | Aguinaga-Barrilero, Ana, Castro-Sánchez, Patricia, Juárez, Ignacio, Gutiérrez-Calvo, Alberto, Rodríguez-Pérez, Noelia, Lopez, Adela, Gómez, Remedios, Martin-Villa, José M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737443/ https://www.ncbi.nlm.nih.gov/pubmed/33354577 http://dx.doi.org/10.1155/2020/1039458 |
Ejemplares similares
-
IGSF4 is a novel TCR ζ-chain–interacting protein that enhances TCR-mediated signaling
por: Kim, Hye-Ran, et al.
Publicado: (2011) -
The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain
por: Kirchgessner, Henning, et al.
Publicado: (2001) -
Role of the Multiple T Cell Receptor (TCR)-ζ Chain Signaling Motifs in Selection of the T Cell Repertoire
por: Shores, Elizabeth W., et al.
Publicado: (1997) -
A subset of memory effector T cells in peripheral blood defined by differential expression of the TCR-ζ chain
por: Zhang, Z, et al.
Publicado: (2003) -
ZAP-70 Association with T Cell Receptor ζ (TCRζ): Fluorescence Imaging of Dynamic Changes upon Cellular Stimulation
por: Sloan-Lancaster, Joanne, et al.
Publicado: (1998)