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Nonclassical Axis of the Renin-Angiotensin System and Neprilysin: Key Mediators That Underlie the Cardioprotective Effect of PPAR-Alpha Activation during Myocardial Ischemia in a Metabolic Syndrome Model

The activation of the renin-angiotensin system (RAS) participates in the development of metabolic syndrome (MetS) and in heart failure. PPAR-alpha activation by fenofibrate reverts some of the effects caused by these pathologies. Recently, nonclassical RAS components have been implicated in the path...

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Detalles Bibliográficos
Autores principales: Sánchez-Aguilar, María, Ibarra-Lara, Luz, del Valle-Mondragón, Leonardo, Soria-Castro, Elizabeth, Torres-Narváez, Juan Carlos, Carreón-Torres, Elizabeth, Sánchez-Mendoza, Alicia, Rubio-Ruíz, María Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737465/
https://www.ncbi.nlm.nih.gov/pubmed/33354204
http://dx.doi.org/10.1155/2020/8894525