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Zika Virus-Like Particles Bearing a Covalent Dimer of Envelope Protein Protect Mice from Lethal Challenge

Zika virus (ZIKV) envelope (E) protein is the major target of neutralizing antibodies in infected hosts and thus represents a candidate of interest for vaccine design. However, a major concern in the development of vaccines against ZIKV and the related dengue virus is the induction of cross-reactive...

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Detalles Bibliográficos
Autores principales: De Lorenzo, Giuditta, Tandavanitj, Rapeepat, Doig, Jennifer, Setthapramote, Chayanee, Poggianella, Monica, Sanchez-Velazquez, Ricardo, Scales, Hannah E., Edgar, Julia M., Kohl, Alain, Brewer, James, Burrone, Oscar R., Patel, Arvind H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737734/
https://www.ncbi.nlm.nih.gov/pubmed/33028720
http://dx.doi.org/10.1128/JVI.01415-20