TFE3 activation in a TSC1‐altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms

Perivascular epithelioid cell tumors (PEComas) form a family of rare mesenchymal neoplasms that typically display myomelanocytic differentiation. Upregulation of mTOR signaling due the inactivation of TSC1/2 (Tuberous Sclerosis 1 and 2) is believed to be a key oncogenic driver in this disease. Recen...

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Detalles Bibliográficos
Autores principales: Schmiester, Maren, Dolnik, Anna, Kornak, Uwe, Pfitzner, Berit, Hummel, Michael, Treue, Denise, Hartmann, Arndt, Agaimy, Abbas, Weyerer, Veronika, Lekaj, Anja, Brakemeier, Susanne, Peters, Robert, Öllinger, Robert, Märdian, Sven, Bullinger, Lars, Striefler, Jana Käthe, Flörcken, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737753/
https://www.ncbi.nlm.nih.gov/pubmed/33180365
http://dx.doi.org/10.1002/cjp2.187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737753/
https://www.ncbi.nlm.nih.gov/pubmed/33180365
http://dx.doi.org/10.1002/cjp2.187

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