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DynaMut2: Assessing changes in stability and flexibility upon single and multiple point missense mutations

Predicting the effect of missense variations on protein stability and dynamics is important for understanding their role in diseases, and the link between protein structure and function. Approaches to estimate these changes have been proposed, but most only consider single‐point missense variants an...

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Detalles Bibliográficos
Autores principales: Rodrigues, Carlos H.M., Pires, Douglas E.V., Ascher, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737773/
https://www.ncbi.nlm.nih.gov/pubmed/32881105
http://dx.doi.org/10.1002/pro.3942