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PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence
Enhancers are powerful and versatile agents of cell-type specific gene regulation, which are thought to play key roles in human disease. Enhancers are short DNA elements that function primarily as clusters of transcription factor binding sites that are spatially coordinated to regulate expression of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737992/ https://www.ncbi.nlm.nih.gov/pubmed/33320871 http://dx.doi.org/10.1371/journal.pone.0243791 |