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PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence

Enhancers are powerful and versatile agents of cell-type specific gene regulation, which are thought to play key roles in human disease. Enhancers are short DNA elements that function primarily as clusters of transcription factor binding sites that are spatially coordinated to regulate expression of...

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Detalles Bibliográficos
Autores principales: Mills, Caitlin, Muruganujan, Anushya, Ebert, Dustin, Marconett, Crystal N., Lewinger, Juan Pablo, Thomas, Paul D., Mi, Huaiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737992/
https://www.ncbi.nlm.nih.gov/pubmed/33320871
http://dx.doi.org/10.1371/journal.pone.0243791