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Prevention of oxaliplatin-related neurotoxicity by ω-3 PUFAs: A double-blind randomized study of patients receiving oxaliplatin combined with capecitabine for colon cancer

BACKGROUND: Peripheral neurotoxicity (PN) is a frequent side effect of oxaliplatin treatment, and also is its dose-limiting toxicity. Studies have confirmed that ω-3 polyunsaturated fatty acids (ω-3 PUFAs) had a neuroprotective effect. However, the efficacy of ω-3 PUFAs on the prevention of oxalipla...

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Detalles Bibliográficos
Autores principales: Zhang, Xinjie, Chen, Haitao, Lu, Yi, Xu, Chao, Yao, Wang, Xu, Lu, Zhang, Runzhe, Zhang, Liping, Yao, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738088/
https://www.ncbi.nlm.nih.gov/pubmed/33327312
http://dx.doi.org/10.1097/MD.0000000000023564