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Adenovirus vectored IFN-α protects mice from lethal challenge of Chikungunya virus infection

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that is responsible for numerous large and geographical epidemics, causing millions of cases. However, there is no vaccine or therapeutics against CHIKV infection available. Interferon-alpha (IFN-α) has been shown to produce potent antiviral res...

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Detalles Bibliográficos
Autores principales: Chen, Huixin, Min, Nyo, Ma, Luyao, Mok, Chee-Keng, Chu, Justin Jang Hann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738163/
https://www.ncbi.nlm.nih.gov/pubmed/33270642
http://dx.doi.org/10.1371/journal.pntd.0008910