Reduction of elevated proton leak rejuvenates mitochondria in the aged cardiomyocyte

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Aging-associated diseases, including cardiac dysfunction, are increasingly common in the population. However, the mechanisms of physiologic aging in general, and cardiac aging in particular, remain poorly understood. Age-related heart impairment is lacking a clinically effective treatment. Using the...

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Detalles Bibliográficos
Autores principales: Zhang, Huiliang, Alder, Nathan N, Wang, Wang, Szeto, Hazel, Marcinek, David J, Rabinovitch, Peter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738186/
https://www.ncbi.nlm.nih.gov/pubmed/33319746
http://dx.doi.org/10.7554/eLife.60827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738186/
https://www.ncbi.nlm.nih.gov/pubmed/33319746
http://dx.doi.org/10.7554/eLife.60827

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