Temperature dependence of the SARS-CoV-2 affinity to human ACE2 determines COVID-19 progression and clinical outcome

The SARS-CoV-2 virus and its homolog SARS-CoV penetrate human cells by binding of viral spike protein and human angiotensin converting enzyme II (ACE2). SARS-CoV causes high fever in almost all patients, while SARS-CoV-2 does not. Moreover, analysis of the clinical data revealed that the higher body...

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Detalles Bibliográficos
Autores principales: Zhou, Zhonghua, Yang, Ziyi, Ou, Junxian, Zhang, Hong, Zhang, Qiwei, Dong, Ming, Zhang, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738279/
https://www.ncbi.nlm.nih.gov/pubmed/33343834
http://dx.doi.org/10.1016/j.csbj.2020.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738279/
https://www.ncbi.nlm.nih.gov/pubmed/33343834
http://dx.doi.org/10.1016/j.csbj.2020.12.005

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