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Lycorine, a non-nucleoside RNA dependent RNA polymerase inhibitor, as potential treatment for emerging coronavirus infections

Background: Highly effective novel treatments need to be developed to suppress emerging coronavirus (CoV) infections such as COVID-19. The RNA dependent RNA polymerase (RdRp) among the viral proteins is known as an effective antiviral target. Lycorine is a phenanthridine Amaryllidaceae alkaloid isol...

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Detalles Bibliográficos
Autores principales: Jin, Young-Hee, Min, Jung Sun, Jeon, Sangeun, Lee, Jihye, Kim, Seungtaek, Park, Tamina, Park, Daeui, Jang, Min Seong, Park, Chul Min, Song, Jong Hwan, Kim, Hyoung Rae, Kwon, Sunoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier GmbH. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738280/
https://www.ncbi.nlm.nih.gov/pubmed/33376043
http://dx.doi.org/10.1016/j.phymed.2020.153440