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Repurposing of metformin and colchicine reveals differential modulation of acute and chronic kidney injury

Acute kidney injury (AKI) is a major health problem affecting millions of patients globally. There is no effective treatment for AKI and new therapies are urgently needed. Novel drug development, testing and progression to clinical trials is overwhelmingly expensive. Drug repurposing is a more cost-...

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Detalles Bibliográficos
Autores principales: El-Rashid, Maryam, Nguyen-Ngo, Danny, Minhas, Nikita, Meijles, Daniel N., Li, Jennifer, Ghimire, Kedar, Julovi, Sohel, Rogers, Natasha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738483/
https://www.ncbi.nlm.nih.gov/pubmed/33319836
http://dx.doi.org/10.1038/s41598-020-78936-5