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Repurposing of metformin and colchicine reveals differential modulation of acute and chronic kidney injury
Acute kidney injury (AKI) is a major health problem affecting millions of patients globally. There is no effective treatment for AKI and new therapies are urgently needed. Novel drug development, testing and progression to clinical trials is overwhelmingly expensive. Drug repurposing is a more cost-...
Autores principales: | El-Rashid, Maryam, Nguyen-Ngo, Danny, Minhas, Nikita, Meijles, Daniel N., Li, Jennifer, Ghimire, Kedar, Julovi, Sohel, Rogers, Natasha M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738483/ https://www.ncbi.nlm.nih.gov/pubmed/33319836 http://dx.doi.org/10.1038/s41598-020-78936-5 |
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