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A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite
Snakebite is a medical emergency causing high mortality and morbidity in rural tropical communities that typically experience delayed access to unaffordable therapeutics. Viperid snakes are responsible for the majority of envenomings, but extensive interspecific variation in venom composition dictat...
Autores principales: | Albulescu, Laura-Oana, Xie, Chunfang, Ainsworth, Stuart, Alsolaiss, Jaffer, Crittenden, Edouard, Dawson, Charlotte A., Softley, Rowan, Bartlett, Keirah E., Harrison, Robert A., Kool, Jeroen, Casewell, Nicholas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738508/ https://www.ncbi.nlm.nih.gov/pubmed/33323937 http://dx.doi.org/10.1038/s41467-020-19981-6 |
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