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Suppression of poised oncogenes by ZMYND8 promotes chemo-sensitization

The major challenge in chemotherapy lies in the gain of therapeutic resistance properties of cancer cells. The relatively small fraction of chemo-resistant cancer cells outgrows and are responsible for tumor relapse, with acquired invasiveness and stemness. We demonstrate that zinc-finger MYND type-...

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Detalles Bibliográficos
Autores principales: Mukherjee, Shravanti, Adhikary, Santanu, Gadad, Shrikanth S., Mondal, Payel, Sen, Sabyasachi, Choudhari, Ramesh, Singh, Vipin, Adhikari, Swagata, Mandal, Pratiti, Chaudhuri, Soumi, Sengupta, Amrita, Lakshmanaswamy, Rajkumar, Chakrabarti, Partha, Roy, Siddhartha, Das, Chandrima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738522/
https://www.ncbi.nlm.nih.gov/pubmed/33323928
http://dx.doi.org/10.1038/s41419-020-03129-x