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Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection

BACKGROUND: Previously, we characterized subtypes of pancreatic ductal adenocarcinoma (PDAC) on computed-tomography (CT) scans, whereby conspicuous (high delta) PDAC tumors are more likely to have aggressive biology and poorer clinical outcomes compared to inconspicuous (low delta) tumors. Here, we...

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Detalles Bibliográficos
Autores principales: Zaid, Mohamed, Elganainy, Dalia, Dogra, Prashant, Dai, Annie, Widmann, Lauren, Fernandes, Pearl, Wang, Zhihui, Pelaez, Maria J., Ramirez, Javier R., Singhi, Aatur D., Dasyam, Anil K., Brand, Randall E., Park, Walter G., Rahmanuddin, Syed, Rosenthal, Michael H., Wolpin, Brian M., Khalaf, Natalia, Goel, Ajay, Von Hoff, Daniel D., Tamm, Eric P., Maitra, Anirban, Cristini, Vittorio, Koay, Eugene J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738633/
https://www.ncbi.nlm.nih.gov/pubmed/33344245
http://dx.doi.org/10.3389/fonc.2020.596931