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DriveWays: a method for identifying possibly overlapping driver pathways in cancer

The majority of the previous methods for identifying cancer driver modules output nonoverlapping modules. This assumption is biologically inaccurate as genes can participate in multiple molecular pathways. This is particularly true for cancer-associated genes as many of them are network hubs connect...

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Detalles Bibliográficos
Autores principales: Baali, Ilyes, Erten, Cesim, Kazan, Hilal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738685/
https://www.ncbi.nlm.nih.gov/pubmed/33319839
http://dx.doi.org/10.1038/s41598-020-78852-8